Provide details of all prescription and non-prescription drugs you are taking presently, including nutritional supplements or herbal preparations as colchicine can affect the absorption of certain food and vitamins in your body for example, vitamin b12.
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Colchicine is contraindicated in patients with renal or hepatic impairment who are taking a P-gp inhibitore.gciclosporinverapamil or quinidineor a strong CYP3A4 inhibitore.gritonaviratazanavirindinavirclarithromycintelithromycinitraconazole or ketaconazolesee section 4.3
There were no studies of the effects of colchicine capsules on fertilityHoweverpublished nonclinical studies have demonstrated that colchicine-induced disruption of microtubule formation affects meiosis and mitosisPublished reproductive studies with colchicine reported abnormal sperm morphology and reduced sperm counts in malesand interference with sperm penetrationsecond meiotic divisionand normal cleavage in females.
Colchicine capsules are not an analgesic medication and should not be used to treat pain from other causes.
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therefore, it was the only plant of the three made fertile by colchicine–the others were unmodified by the treatment.